Exposure at the Air/Liquid Interface

In response to the scientific need to expose in physiologically relevant conditions, the VITROCELL® exposure devices have been specifically designed to enable direct exposure of mammalian cells or tissue at the Air/Liquid Interface. Here the cell cultures are not covered with media as opposed to submerged conditions which cause an undesired inter­action of the formerly airborne substances with the culture media. Cell systems cultivated on membrane inserts are exposed at the Air/Liquid Interface (ALI) so that the test substances are received directly. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.

VITROCELL® 12/12 Climatic Chamber with Docking Station

The VITROCELL 12/12 System and it’s docking station are integrated in a Climatic Chamber which is heated at 37° C. The heating of the entire system avoids condensation of aerosols provided by a liquid aerosol generator or by e-cigarettes /electronic nicotine delivery systems (ENDS). Furthermore, the constant temperature enables a perfect supply of humidified air (normally 85 % R. H.)

Key Features:

• Dimensions (L x W x H): 1 280 x 900 x 870 (open 1 350) mm
• Supplied with dynamic double-jet dilution system for 3 dilutions @ 3 replicates and 1 clean air control @ 3 replicates
• Integrated Humidification Station
• Integrated aerosol distribution system made of stainless steel/VITROGLIDE surface
• Climatic Chamber with temperature monitoring
• Unique quick-connect system for easier handling